However, you shouldnt interpret them as supportive of any health benefit. He J, Si X, Ji M, et al. View abstract. People use rhubarb for diarrhea, stomach pain, indigestion, symptoms of menopause,. Scientists tested the rhapontic rhubarb extract in a placebo-controlled trial and found that it reduced menopause symptoms significantly more than placebo over 12 weeks ( Alternative Therapies in Health and Medicine, Jan-Feb., 2009). As its constituents belong to the class of natural hydroxystilbenes, concerns have been raised about possible health risks similar to those known for the estrogenic diethylstilbestrol. SSO.Schweiz.Monatsschr.Zahnheilkd. Menopause. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. My thesis aimed to study dynamic agrivoltaic systems, in my case in arboriculture. Black Cohosh Side Effects Stomach upset. The health effects of the other forms of rhubarb have not been studied extensively. Confirmation of the efficacy of ERr 731 in perimenopausal women with menopausal symptoms. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Xiao-dong Z, An-yu W, Shao-feng W, and et al. More recently, it was uncovered that Rhubarb can also alleviate symptoms of menopause and sepsis, a life-threatening response to infection [4, 5, 6, 7]. All of our content is written by scientists and people with a strong science background. Epub 2006 Oct 17. Li, T. [Rhubarb in the treatment of viral hepatitis and its mechanism of action]. In case you hadnt noticed (fat chance! People with liver disease, a high risk of stroke or blood clots, or seizure disorders. Phone: +91-712-2543006. Please see our Medical Disclaimer for more information. 2006;30:1737-41. Do not take black cohosh if you are taking cisplatin (Platinol-AQ). This might reduce the effects of cyclosporine. View abstract. WebMD does not provide medical advice, diagnosis or treatment. Bi, Z. Q. It includes rhaponticin and desoxyrhaponticin, which are able to stimulate estrogen receptors. Your email address will not be published. Would you like email updates of new search results? Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Menopause is the point when a woman no longer has menstrual periods for at least 12 months. Epub 2009 Jul 3. All rights reserved. The full list of currently known side effects of black cohosh use includes: abnormal or increased vaginal discharge. 2017;149(2):55-60. doi: 10.1016/j.medcli.2016.12.031. As women grow older, they experience changes in their physical, emotional and sexual health. Jiao D, Shen X, Gao Y, and et al. We believe that the most accurate information is found directly in the scientific source. Bookshelf It also reduced the length of the hospital stay and the need for IV fluids better than just antibiotics (Ceftizoxime sodium or Levofloxacin) [35]. View abstract. Rhubarb leaves are possibly unsafe. No clinical evidence supports the use of rhubarb for any of the conditions listed in this section. Phytomedicine. *All individuals are unique. Yang, N., Liu, X., and Lin, Q. In addition to experiencing fewer hot flashes, women taking Siberian rhubarb extract can expect broad spectrum improvements in menopause symptoms, including better mood and better sleep. Rhubarb can cause some side effects such as stomach and intestinal pain, watery diarrhea, nausea, vomiting, rash, and uterine contractions. Effects of the special extract ERr 731 from Rheum rhaponticum on estrogen-regulated targets in the uterotrophy model of ovariectomized rats. Chinese rhubarb helped stop digestive tract bleeding in a study of 312 hospitalized people [33]. No medical claims are implied in this content, and the information herein is not intended be used for self-diagnosis or self-treatment of any condition. Anxiety, stress, brain fog, and hot flashes have diminished. The same effect might not be observed in other populations. The main active ingredient here is organic, but that doesnt mean its not a potent substance. Chinese rhubarb is often combined with other herbs and dietary changes to achieve synergistic effects in TCM. Basu TK, Ooraikul B, and Garg M. The lipid-lowering effects of rhubarb stalk fiber: A new source of dietary fiber. Journal of Chinese Materia Medica 1989;14(8):501-3, 512. Combinatorial effects of the phytoestrogen genistein and of estradiol in uterus and liver of female Wistar rats. View abstract. A clinical study on compound da huang (radix et Rhizoma rhei) preparations for improvement of senile persons' memory ability. Kaszkin-Bettag M, Beck S, Richardson A, Heger PW, Beer AM. 3 E Evergreen Road #1193, New City, NY 10956 Taking a rhubarb root extract by. Phytoestrogens mimic estrogen in the body by binding to estrogen receptors. NCI CPTC Antibody Characterization Program. Complement Ther Med. View abstract. They ask that you first approach the company that sold you the product for a refund. After 84 days, the rhubarb extract reduced menopausal symptoms by 60%. The combination worked by constricting the blood vessels, increasing platelets, improving platelet clumping, and reducing bleeding time [34]. Epub 2021 Apr 27. There is a search provided where you can find either an in-person or an online shop to buy Estroven, presumably at the price they have listed. In 112 patients, rhubarb-containing Chinese herbal mixture (Tangshen Recipe) with insulin treatment was equally effective as conventional anti-diabetes drugs [19]. Zhang H, Jiang M, Gao L, Lin Z. Many of the Chinese rhubarb articles were conducted in China with Chinese people. Taking another Chinese herbal combination with rhubarb, Rheum E, helped slow the progression of chronic kidney failure in a clinical trial of 30 people. Zhang, G. and el Nahas, A. M. The effect of rhubarb extract on experimental renal fibrosis. Please follow the instructions listed below to upload your electronic proof of purchase. This benefit of rhubarb is mainly due to the presence of dietary fibers in them. This has helped me with some of the menopause symptoms. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1996;16(11):649-651. Jiao, D. H. [Alcoholic extract tablet of rhubarb in treating acute upper gastrointestinal hemorrhage]. The effects of rhubarb alone remain obscure. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. View abstract. In a clinical trial of 109 women approaching menopause, a rhapontic rhubarb supplement (ERr 731) reduced improved the quality of life and reduced symptoms such as the frequency and severity of hot flashes. Zhao D, Feng SX, Zhang HJ, et al. Other anthraquinone compounds such as aloe-emodin, emodin, and rhein have antibacterial properties. Taking rhubarb with other stimulant laxatives might cause more diarrhea and very low potassium levels. Rhapontic Rhubarb Root Extract, Dicalcium Phosphate, and Riboflavin. In a study with over 1,000 patients with sepsis, Chinese rhubarb reduced fungal infections, especially when combined with adequate nutrition (via stomach tubes or IV) [37]. This supplement has the key ingredient Rhapontic Rhubarb Root Extract, which includes the key active ingredients rhaponticin and desoxyrhaponticin. Goel, V., Cheema, S. K., Agellon, L. B., Ooraikul, B., and Basu, T. K. Dietary rhubarb (Rheum rhaponticum) stalk fibre stimulates cholesterol 7 alpha-hydroxylase gene expression and bile acid excretion in cholesterol-fed C57BL/6J mice. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. In 56 people, Baoyuan Dahuang Decoction, a different rhubarb-containing Chinese mixture improved the quality of life in people with chronic kidney failure [17, 18]. Der Freie Zahnarzt 1997;9:76-80. Efficacy of Natural Formulation Containing Activated Charcoal, Calcium Sennosides, Peppermint Oil, Fennel Oil, Rhubarb Extract, and Purified Sulfur (Nucarb) in Relieving Constipation. View abstract. Rhapontic rhubarb is used for many of the same reasons as black cohosh, and it's the active ingredient in the popular menopause supplement Estroven. In another study, Chinese rhubarb with Captopril also normalized levels of a marker of kidney dysfunction (IL-6) in the urine of people with chronic kidney failure [16]. Federal government websites often end in .gov or .mil. Black cohosh side effects include: Stomach upset Rash Cramping Headaches Vaginal spotting or bleeding 2 Potential soy side effects include: and check out those references. It claims that this produces no adverse side effects. This site needs JavaScript to work properly. Bahtiar A, Setyowati HT, Mahanani RR, Wati A, Arsianti A, Fadilah F. J Adv Pharm Technol Res. Rhubarb decreased the systemic exposure of cyclosporine, a probe substrate of P-glycoprotein and CYP 3A. 2005;25(8):744-747. A Chinese herbal with rhubarb (Jiangzhuoqinggan) was as effective as the standard drug, irbesartan, at reducing both systolic and diastolic blood pressure [42]. 2008 Nov-Dec;14(6):32-8. Rash. Chinese Journal of Integrated Traditional and Western Medicine 2001;7(3):186-189. Am J Forensic Med Pathol. Efficacy and safety of a special extract of Rheum rhaponticum (Err 731) in perimenopausal women with climacteric complaints: a 12-week randomized, double-blind, placebo-controlled trial. tic r-pn-tik. It appears to have some benefits for the treatment of menopause symptoms ( 26 ). Kang, Z., Bi, Z., Ji, W., Zhao, C., and Xie, Y. abnormal heartbeat or altered blood pressure, typically lowered. J.Tradit Chin Med 1980;21(11):18. In 145 patients, a sage and Chinese rhubarb (23 mg/g) topical cream had a similar efficacy as a common herpes medication (Zovirax) at healing herpes sores [50]. If the egg is released and there is a viable sperm waiting to fertilize the egg, you can, and will, get pregnant. View abstract. Rhubarb Reduces Hot Flashes The results, published in the journal Menopause, showed that treatment with the rhubarb extract significantly reduced the frequency and severity of hot flashes in the perimenopausal women compared with the placebo. 2001;24(3):264-267. In 78 people with SIRS, Chinese rhubarb powder added to the conventional treatment helped cure the disease, and reduced organ damage and deaths. On this basis, extracts of rhubarb have been tried for control of menopausal symptoms. 1991;11(9):547-9, 518. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Contains clinically proven rhapontic rhubarb faster menopause relief. Its root and underground stem are used in traditional Chinese medicine combinations. Li, L. S. and Liu, Z. H. [Clinical and experimental studies of rheum on preventing progression of chronic renal failure] (Chinese). 2023 Feb 14;15(4):949. doi: 10.3390/nu15040949. The strength of the evidence from these trials is limited by small sample size, varying herbal formulas used, and the high risk of bias. Similarly, in a clinical trial of 83 people with clogged arteries, a Chinese rhubarb preparation (50 mg/kg) lowered total and LDL cholesterol and also improved artery health [40]. Cureus 2021;13(10):e18419. Hua Xi.Yi.Ke.Da.Xue.Xue.Bao. It was given alongside conventional treatment [11]. Rhubarb can work as a laxative. View abstract. Estroven Complete is an organic supplement that aims to treat the symptoms associated with menopause and perimenopause. 2017 Apr;62(4):1043-1050. doi: 10.1007/s10620-017-4464-7. Wan B, Fu H, Yin J, Xu F. Efficacy of rhubarb combined with early enteral nutrition for the treatment of severe acute pancreatitis: a randomized controlled trial. Rhubarb has the potential to boost liver function, reduce fatty liver, and improve bile flow alongside conventional treatments. Scientific studies have confirmed numerous benefits that range from gut, liver and kidney protection to lowering inflammation and cholesterol. 2021;1308:309-352. doi: 10.1007/978-3-030-64872-5_22. Pharmacology 1976;14:48-61. Various Chinese herbal remedies containing rhubarb show benefits for people with kidney failure by reducing overall symptoms and the buildup of waste products. Sun, D. A. The company states that you can save up to 20% if you order monthly shipments. Ren, S. [Role of a virus in hemorrhagic pancreatitis and the therapeutic effect of rhubarb]. it banned the export of the seeds to block the growing of the plant elsewhere. 1999;19(4):218-220. Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. There are two good reasons not to eat them in summer. Chinese rhubarb combined with mineral powder and blood purification was more effective at treating severe herbicide poisoning than the standard procedure. View abstract. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. Zhong.Xi.Yi.Jie.He.Za Zhi. By activating this estrogen receptor, rhubarb extract has been studied and clinically demonstrated to . Xu, F. and Fu, H. M. [Qing-shen tiao-zhi tablet in the treatment of hyperlipemia in the middle and old aged]. Crocket SD, Wani S, Gardner TB, et al. Rhubarb can be found in various forms, usually made from the roots and rhizomes of Chinese rhubarb [3, 4]: The below doses may not apply to you personally. Cochrane Database Syst Rev. Still, most benefits lack solid clinical evidence. Taking rhubarb and cyclosporine together might reduce the levels of cyclosporine in the blood. Hepatobiliary.Pancreat.Dis.Int 2004;3(3):375-380. Lu L, Li HQ, Fu DL, Zheng GQ, Fan JP. 8600 Rockville Pike It includes rhaponticin and desoxyrhaponticin, which are able to stimulate estrogen receptors. Nutrition Reserach 1993;13:1017-1024. Leave a review and share your experience with others. Comment * document.getElementById("comment").setAttribute( "id", "a269cd1e8bbff3968ad1d173ca7d8400" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. Postmenopause is the stage after menopause. Some common varieties of rhubarb include [1, 7+]: The most commonly used parts of the plant for medicinal purposes are the roots and rhizomes, which contain [6, 7+, 3+, 8]: Rhubarb contains toxic compounds known as salts of oxalic acid/oxalates, which are not broken down during cooking. View abstract. A low dose of Chinese rhubarb (0.75 g/day) was able to reduce the rates of this condition in 333 pregnant women at high risk [43]. Zhang, Z. J., Cheng, W. W., and Yang, Y. M. [Low-dose of processed rhubarb in preventing pregnancy induced hypertension]. Special Precautions and Warnings It's usually well-tolerated. In a clinical trial of 30 people, Chinese rhubarb (10 g/day, fed nasally 3x/day) added to the normal treatment improved gut function [31]. Chen Q, Han G, Zhuang X, and et al. Rhubarb root and rhizome-based Chinese herbal prescriptions for acute ischemic stroke: a systematic review and meta-analysis. Song, H., Wang, Z., and Zhang, F. [Investigation of urinary interleukin-6 level in chronic renal failure patients and the influence of Rheum palmatum in treating it]. Forsch Komplementarmed Klass Naturheilkd 2001;8:373-82. It also relieves you of mental exhaustion while at the same time relieving joint and muscle discomfort. The leaves of Rhubarb are toxic and should not be consumed. Helps relieve 11 common & uncommon menopausal discomforts. J Crit Care. This is the end of a womans reproductive years. Up to 66% reduction in irritability and mood swings. View abstract. Further research is warranted. Ethnobotanical Uses, Phytochemistry and Pharmacology of Different Rheum Species (Polygonaceae): A Review. In a clinical trial of 126 people with severe inflammation of the pancreas, the use of Chinese rhubarb powder (15 g, 1 2x/day) with a specific nutrition plan lowered inflammation, disease severity, and liver and kidney damage [26]. More than 900 milligrams a day of black cohosh is considered an overdose. A: The product cannot be purchased directly through the manufacturers website, but theres a search on the site that will direct you to either an in-person or an online location to purchase this supplement. JPEN J Parenter Enteral Nutr. (Chinese Journal of Modern Developments in Traditional Medicine) 1990;10(3):150-152, 131-132. What are the side effects of rhubarb? Your email address will not be published. 2005;3(3):195-198. Mao QL. Researchhas shown that rhapontic rhubarb can be an effective remedy for some of the symptoms of menopause, although the mechanism isnt 100% clear. Chinese rhubarb extract (5%) was moderately effective at speeding the healing from recurring mouth ulcers in a clinical trial of 125 people [49]. Unauthorized use of these marks is strictly prohibited. I have a brand new unopened box of it and if you would like it text me at 412 265-5865 or email me at
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