932 University of Pittsburgh jobs. Search for more papers by this author Pittsburgh, PA 15261. Fluorescent protein biosensors applied to microphysiological systems. Xiang-Qun (Sean) Xie - Professor, U of Pittsburgh, Dept of Pharmaceutical Sciences and Drug Discovery Institute, Associate Dean of the School of Pharmacy, Director of CDAR and CCGS centers Ph.D., Medicinal Chemistry, School of Pharmacy, University of Connecticut, CT Clinical and Research Interests: I am the Director of the University of Pittsburgh Drug Discovery Institute (UPDDI) where we have three major activities: 1) drug discovery programs applying quantitative systems pharmacology (QSP) to liver diseases, metastatic breast cancer, and neurodegenerative diseases; 2) drug discovery projects with collaborators where we apply whatever technology is . The University of Pittsburgh Policy Review Committee will review University policies on patents and copyrights, conflict of interest, and responsible conduct of research with the intention of making recommendations that will improve the ability of our faculty to work productively with external partners and effectively translate research in ways that will support the University's shared goal . I am also developing computational tools to identify and quantify heterogeneity. Pittsburgh Chemistry Faculty Web Page. Computational & Systems Biology Dept School of Medicine, University of Pittsburgh Associate Director, UP Drug Discovery Institute Seminar on:November 9th ,2021. Our community is ready to answer. The primary strategy is to combine expertise in computation and systems biology at Pitt and Carnegie Mellon University with crucial patient samples from UPMC. Under the leadership of D. Lansing Taylor, the Drug Discovery Institute at the University of Pittsburgh is optimizing the discovery and development of new molecular entities through collaborations among faculty members, academic centers, corporations, and government agencies, together with innovations in chemistry, molecular biophysics, and . 2 Department of Medicine, Division of Endocrinology and Metabolism, University of Pittsburgh, Pittsburgh, PA 15261, USA. Drug Discovery Institute The University of Pittsburgh Drug Discovery Institute (UPDDI) brings together faculty and graduate students from the Schools of Medicine, Arts & Sciences, Pharmacy, and Public Health in pursuit of a common goal: to identify small molecules that will ultimately result in drug therapy treatments for orphan and neglected . University of Pittsburgh Diabetes Institute Quantum One Building Suite E290 2 Hot Metal Street Pittsburgh, PA 15203 Administrative/ Research Office: (412) 864-0157 Patient/ Clinical Inquiries: (412) 586-9700 3550 Terrace Street. Dr. University students and faculty, institute members, and independent researchers Corporate, government, or NGO researcher Technology or product developers, R&D specialists, and government or NGO . Hello! The Drug Discovery Institute explores new approaches to the discovery of novel therapeutics, in addition to supporting more traditional approaches. (2)Department of Computational and Systems Biology, University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA, USA. "The summer before my senior year of high school, I became interested in research following an experience at the University of Pittsburgh's Drug Discovery Institute," said Davis. Previously, she held the role of Business Development Manager in the Innovation Institute and Drug Discovery Institute at the University of Pittsburgh. The Drug Discovery Institute at the University of Pittsburgh on Academia.edu Abstract The next generation of chemical toxicity testing will use organs-on-chips (OoCs)—3D cultures of heterotypic cells with appropriate extracellular matrices to better approximate the in vivo cellular microenvironment. University of Pittsburgh Drug Discovery Institute, Pittsburgh, Pennsylvania. Author information: (1)University of Pittsburgh Drug Discovery Institute, Pittsburgh, PA 15260, USA University of Pittsburgh Department of Computational & Systems Biology, Pittsburgh . Bradley Yates, PhD 2013 (Postdoc with Sachdev Sidhu, University of Toronto) Suvrajit Maji, PhD 2012 (Postdoc with Joachim Frank, Columbia University) Nina Senutovitch, PhD 2012 (Postdoc at University of Pittsburgh Drug Discovery Institute) Qi Yan, PhD 2012 (Biology Director, Sharp Edge Labs) The city of Pittsburgh is one of the "most livable" cities in the US . He also serves as a co-Director of the University of Pittsburgh Drug Discovery Institute and is a member of the University of Pittsburgh Cancer Institute. Pittsburgh Chemistry Faculty Web Page. sciVelo accelerates life and health sciences commercial translation at the University of Pittsburgh. The grant, led by Dr. Mark Schurdak , associate professor of computational and systems biology at Pitt's School of Medicine and director of operations at the DDI, was . Vice Director, Zandrea Ambrose, PhD. . University of Pittsburgh Drug Discovery Institute. University of Pittsburgh. 7 Okinawa Institute of Science and Technology, Okinawa, Japan. . Pittsburgh, PA 15261. 11 people answered. Formal interactions with the University of Pittsburgh Cancer Institute, the Center for Neuroscience, the Drug Discovery Institute, the Structural Biology Imaging Center, the Vascular Medicine Institute, and the Division of Clinical Pharmacology provide a broad multidisciplinary training in basic and translational molecular pharmacology. Gao's laboratory is well supported by extramural funding. Ms. Phillips joined the University of Pittsburgh in 2001 and has served as a Research Technician in the Departments of Endocrinology and Immunology. 2 School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, China. Research Interest: My research interest lies in investigating the mechanism and treatment of human malignancies. Director, Institute for Infection, Inflammation, and Immunity in Children (i4Kids), UPMC Children's Hospital of Pittsburgh. In my role as the Director of the University of Pittsburgh Drug Discovery Institute, I have the goal to assist both academic and commercial collaborators to discover and to develop efficacious and safe therapeutics based on the integration of outstanding science, technology and drug discovery/development methods. Dr. Chen joined the Department of Ophthalmology at the University of Pittsburgh in 2017 as an assistant professor. 1 University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA. Email: dltaylor@pitt.edu Office: 10045 BST 3 Phone: 412-648-9200 Drug screening and discovery: The lab has developed several cancer and infection models, and used them in Crispr-Cas9 mediated genome-wide screening . UPMC Hillman Cancer Therapeutics Program (CTP) School of Pharmacy, Department of Pharmaceutical Sciences at Pittsburgh. 412-383-4318 isb@pitt.edu Learn about salary, employee reviews, interviews, benefits, and work-life balance Prof. Claudiu Gradinaru Single-molecule biophysics group,University of Toronto, Mississauga Seminar on: 14th Dec 2021 . luoj@msx.upmc.edu. Harnessing Human Biomimetic Liver MPS Combined My academic interests link large-scale cell, tissue and human, biomimetic, tissue-engineered in vitro disease model profiling with computational and systems biology to optimize drug discovery and diagnostics. University of Pittsburgh: Website: www.researchgate.net /profile /D _Taylor5; D. Lansing Taylor is the Director at the University of Pittsburgh Drug Discovery Institute (UPDDI), Pennsylvania and a faculty member in the Department of Computational and Systems Biology. Shari Murphy, Program Administrator University of Pittsburgh BST3, 5th floor, 5054C 3501 5th Ave., Pgh. Here, we review two other key aspects of how OoCs may advance predictive . Drug Discovery Institute (UPDDI) - High Content Screening (HCS) Imaging Resources . 6 Laboratory for Disease Systems Modeling, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan. A pivotal recent addition is the 10-story, 335,000-square-foot Biomedical Science Tower 3, which houses the Center for Vaccine Research; the Drug Discovery Institute; the structural biology and computational biology programs, which are among the most advanced in the country; the Pittsburgh Institute for Neurodegenerative Diseases; and 10,000 . University of Pittsburgh Drug Discovery Institute Pittsburgh, PA USA . University of Pittsburgh Pittsburgh, PA 15261 PHONE: 412-383-7722 . As the Director of the Drug Institute, I am focusing our . 412-383-4318 isb@pitt.edu Located in the Oakland section of Pittsburgh, the University of Pittsburgh is ranked top-ten in securing NIH funding, and provides a rich environment for interdisciplinary research, strengthened through its affiliation with the University of Pittsburgh Medical Center (UPMC). Director, Institute for Infection, Inflammation, and Immunity in Children (i4Kids), UPMC Children's Hospital of Pittsburgh. Apply to the latest jobs near you. How do you feel about going to work each day at University of Pittsburgh? University of Pittsburgh School of Pharmacy 3501 Terrace St Pittsburgh, PA 15261 . Currently, University Of Pittsburgh Medical Center Heart & Vascular Institute specializes in Internal Medicine, Interventional Cardiology, Nurse Practitioner and Cardiovascular Disease with 9 physicians. He also serves as the Director of the McGowan Institute's Cellular Approaches to Tissue Engineering and Regeneration (CATER) Training Program, Assistant Dean for the Medical Scientist Training Program (MSTP), Associate Director of the University of Pittsburgh Drug Discovery Institute (UPDDI), and is the Founding Director of the NIH, NIDDK . We are so pleased and proud to see that Dr. Hongchun Li is now a Faculty member at Shenzhen Institutes of Advanced Technology, as an Associate Research Professor at the Center for Computer-aided Drug Discovery, Institute of Biomedicine and Biotechnology, Chinese Academy of Sciences. Drug Discovery Institute Pittsburgh Center for Kidney Research Pittsburgh Institute for Neurodegenerative Diseases Shari Murphy, Program Administrator University of Pittsburgh BST3, 5th floor, 5054C 3501 5th Ave., Pgh. 7 Okinawa Institute of Science and Technology, Okinawa, Japan. The Vanderbilt-Pittsburgh Resource for Organotypic Models for Predictive Toxicology (VPROMPT) is a collaboration among researchers at the Vanderbilt University and the University of Pittsburgh Drug Discovery Institute ().). Affiliates. 4 Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America. University of Pittsburgh Drug Discovery Institute The Microphysiology Systems Database (MPS-Db): A platform for aggregating, analyzing, sharing and modeling of in vitro and in vivo safety and efficacy data https://mps.csb.pitt.edu/ Mark Schurdak, PhD Director of Operations, University of Pittsburgh Drug Discovery Institute, The imaging resources at the University of Pittsburgh Drug Discovery Institute (UPDDI) include high content screening (HCS) platforms to extract multi-parameter information from cell and tissue models, as well as engineered small organism models of disease. University of Pittsburgh Drug Discovery Institute Pittsburgh, PA USA. www.upddi.pitt.edu. There are currently 6 active R01s and 1 Sub-project of an active PPG. Swanson School of Engineering, Department of Bioengineering at Pittsburgh. Phone: Human-Computer Interaction Institute - Carnegie Mellon University - School of Computer Science Nov 2011 - Aug 2012 10 months 5000 Forbes Avenue Pittsburgh, PA 15213 Adam Zweifach, Ph.D. University of Connecticut Storrs, CT USA. The University of Pittsburgh Drug Discovery Institute (DDI) is among three institutes in the country to be awarded a grant to establish a new Tissue Chip Testing Center (TCTC). Institute of Translational Bioengineering at Roche in Basel, Switzerland: Timothy Spicer, PhD: The Scripps Research Institute, Jupiter, FL, USA: . Dr. D. Lansing Taylor (Drug Discovery Institute and Dept of Computational and Systems Biology), along with Dr. Vijay Yechoor (Department of Medicine and Director, Diabetes and Beta Cell Biology Center) have received a one year funded initiative to study the effects of COVID-19 on the Diabetic Liver. The Drug Discovery Institute at the University of Pittsburgh on Academia.edu Associate Director, University of Pittsburgh Drug Discovery Institute (UPDDI) Email: smonga@pitt.edu. Mes234@pitt.edu. Pre-Clinical and Research Interests: I am a toxicologist in the Drug Discovery Institute (DDI) with interests in drug induced liver injury (DILI), drug PK, drug efficacy, and the effect of drug treatment on liver disease progression.The DDI has a constructed a 3D, 4-cell type human liver in a microfluidic device that is currently in use for drug safety assessment. Congratulations, Hongchun, we are so happy . Allegheny Foundation Professor of Computational and Systems Biology. . Infectious Diseases, University of Pittsburgh Medical Center, 2005 Research Interest The mission of Dr. Doi's laboratory is to identify and investigate antimicrobial resistance of clinical concern among gram-negative bacterial pathogens. UPMC Hillman Cancer Therapeutics Program (CTP) School of Pharmacy, Department of Pharmaceutical Sciences at Pittsburgh. Aug 2014 - Present7 years 4 months. 6 Laboratory for Disease Systems Modeling, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan. University Centers University Center for International Studies (UCIS) Learning Research and Development Center (LRDC) Center for Philosophy of Science University Center for Social and Urban Research (UCSUR) Other Centers and Institutes Advanced Imaging Center PA 15260. Bahar Lab at the University of Pittsburgh School of Medicine, Dept of Computational and Systems Biology; University of Pittsburgh Drug Discovery Institute, Citation: MC Cobanoglu, ZN Oltvai, DL Taylor, I Bahar. Some of the oncogenes, tumor suppressor genes and fusion genes we characterized in the past have been . Keanu Davis, who is from Pittsburgh, Penn., is majoring in microbiology with minor in sociology at Washington University in St. Louis. Novel Chemistries and Systems Biology Power . Office: University of Pittsburgh Department of Pathology. A320 Langley Hall, University of Pittsburgh Pittsburgh, PA 15260. Pittsburgh Supercomputing Center: Sean Xie: Computational Drug Discovery: Chemogenomics-knowledgebase small molecule probe design and development for target-specific drug discovery: Pitt - Pharmaceutical Sciences/Drug Discovery Institute: Jianhua Xing: Systems Biology 8 Department of Chemical & Petroleum Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA jason.shoemaker@pitt.edu. University of Pittsburgh. Ask a question about working or interviewing at University of Pittsburgh. . Associate Director, University of Pittsburgh Drug Discovery Institute (UPDDI) The University of Pittsburgh is among the nation's most distinguished comprehensive universities, with a wide variety of high-quality programs in both the arts and sciences and professional fields. Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania. Associate Director, University of Pittsburgh Drug Discovery Institute (UPDDI) Questions about University of Pittsburgh. Prior to that, Dr. Ducruet was a Postdoctoral Associate in the Department of Pharmacology at the University of Pittsburgh, where he studied cancer biology and the molecular mechanisms of natural product anticancer agents, as well as collaborated in multiple drug discovery programs. Simulations Plus announced that its DILIsym division and the University of Pittsburgh Drug Discovery Institute jointly received a Phase I SBIR grant. Drug Discovery Institute The University of Pittsburgh Drug Discovery Institute (UPDDI) brings together faculty and graduate students from the Schools of Medicine, Arts & Sciences, Pharmacy, and Public Health in pursuit of a common goal: to identify small molecules that will ultimately result in drug therapy treatments for orphan and neglected . Follow their code on GitHub. Researchers are already working to validate whether OoCs are predictive of toxicity in humans. Dr. Palczewski is a renowned biochemist in vision research who made significant contributions in revealing the molecular structure of the visual pigment rhodopsin, as well as in drug development in blinding disease. Early life and education . 412-624-4831 jbrodsky@pitt.edu. I'm a recent chemical engineering PhD using network and mathematical modeling to study immunoregulation during influenza and SARS-CoV-2 infection. The Institute is at the forefront of the emerging field of quantitative systems pharmacology. University of Pittsburgh Drug Discovery Institute (UPDDI) Ask a Question. The candidate will benefit from the rich biomedical research environment in the University of Pittsburgh, including the UPMC Hillman Cancer Center, the Department of Computational and Systems Biology, the Drug Discovery Institute and the Magee-Women's Research Institute. Senutovitch N (1), Vernetti L (2), Boltz R (1), DeBiasio R (3), Gough A (1), Taylor DL (1). sciVelo's mission is to Engage in Research of Impact by identifying . Crosstalk between macrophages and beta-cells in postnatal beta-cell growth and in diabetes. (3)Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA. Curriculum Vitae. . Vision for the University of PIttsburgh Drug Discovery Institute: Optimizing the discovery and development of new molecular entities through collaborations between faculty, academic centers, corporations and government agencies, together with innovations focused on Quantitative Systems Pharmacology (QSP). University of Pittsburgh. I'll be joining the Lahav Lab at Harvard's Systems Biology department this fall. S-760 Scaife Hall. LEARN MORE about this journal, its editorial scope and how to submit manuscripts. Natalie Dales, Ph.D., Senior Vice President, Chemistry and Drug Discovery Dr. Dales is an accomplished scientist with over 20 years' small molecule drug discovery experience leading and mentoring teams in pharmaceuticals and biotech. Jianhua Luo, MD, PhD*. Office Location: S-422 BST 200 Lothrop Street Pittsburgh PA 15261 Contact Information: Office Telephone: 412-648-8842 Email: smonga@pitt.edu or mongass@upmc.edu Here are some of the ongoing research directions and projects: 1. Adjunct Professor, Director - University of Pittsburgh Drug Discovery Institute, Professor of Computational and Systems Biology - University of Pittsburgh. University students and faculty, institute members, and independent researchers Corporate, government, or NGO researcher Technology or product developers, R&D specialists, and government or NGO . In collaboration with our colleagues at the University of Pittsburgh Drug Discovery Institute and the Department of Chemistry, we have identified the first potent and selective small molecule PKD inhibitor, CID755673, and subsequently developed a class of unique ATP-noncompetitive inhibitors based on this parental compound. University of Pittsburgh Drug Discovery Institute, Department of Computational and Systems Biology, Pittsburgh, PA, USA: Publishing Manager. Shenzhen, China. 200 Lothrop Street, S422 BST. University of Pittsburgh Drug Discovery Institute D. Lansing Taylor, Ph.D. Director, Distinguished Professor and . 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