It helps lower the levels of bad cholesterol (LDL) in the blood. But before using milk thistle, consult with a doctor. How do I get rid of whiteheads on my nose naturally? In the video below, Dr. Eric Berg talks about 8 Benefits of Milk Thistle for the Liver. However, how it affects humans is currently unknown. In fact, people have been using milk thistle as far back as 40 90 AD. High levels of LDL are harmful to the heart. How Long Does Milk Thistle Take to Work. The studies done on animal shows that Milk Thistle when taken during pregnancy did not affect the course of pregnancy, the development of offspring, the cognition of pups, and the long-term treatment did not have any significant effects on the offspring. If youre taking milk thistle for the liver, the recommended daily intake of milk thistle is 150 milligrams, taken one to three times daily. Studies show that dosages up to 700 mg 3 times per day for 24 weeks were well tolerated. As it's well tolerated by your body, you can really take milk thistle oil at any time of day. People who are irritant to certain allergic substances or having a stuffy nose should also avoid milk thistle consumption. However, the results from studies have been mixed, and not all have found milk thistle extract to have a beneficial effect on liver disease. University of Rochester Medical Center: Milk Thistle., National Center for Complementary and Integrative Health: Hepatitis C and Dietary Supplements, Milk Thistle., Lancet Oncology: Milk thistle: early seeds of potential., Huntingtons Outreach Project For Education, at Stanford: About Free Radical Damage., Journal of Natural Products: Silymarin Suppresses Cellular Inflammation By Inducing Reparative Stress Signaling., Journal of the American Medical Association: Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial., Centers for Disease Control and PreventionMorbidity and Mortality Weekly Report: Amanita phalloides Mushroom Poisonings -- Northern California, December 2016.. Milk thistle is a safe supplement that shows potential as a complementary therapy for various conditions, including liver disease, cancer and diabetes. However, human studies are limited and havent yet shown any beneficial effects. It is being researched extensively for its medicinal applications. It has been used for generations as a natural remedy. Researchers from Iran have reported that the flowering plant milk thistle contains a compound called silymarin, which has antioxidant and lipid-lowering properties. Milk thistle works more like a food than a typical drug. As such, you should always purchase milk thistle from a reputable retailer. Consumption of milk thistle refreshes and cleanses the liver by detoxifying harmful pollutants from the body. These cookies will be stored in your browser only with your consent. This website uses cookies to improve your experience while you navigate through the website. All rights reserved. Myths and facts about this essential organ. It has been used for generations as a natural remedy. Make like the Italians but swap your olive oil for a drizzle of milk thistle as a finishing touch. Common Side Effects Although rare, milk thistle may trigger a number of common and mild side effects. Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. Vargas-Mendoza N, ngeles-Valencia M, Madrigal-Santilln EO, Morales-Martnez M, Tirado-Lule JM, Solano-Urrusquieta A, Madrigal-Bujaidar E, lvarez-Gonzlez I, Fregoso-Aguilar T, Morales-Gonzlez , Morales-Gonzlez JA. It may be preferable to take milk thistle in the morning because it helps to kickstart your day and provide you with the antioxidant benefits that milk thistle has to offer. If Milk Thistle is to be used as prescription medicine or along with medicine it is suggested to consult your physician before consuming it to prevent interaction with other medicines. Some people have reported nausea, gas, diarrhea, or loss of appetite. Combining it with other foods helps your body to digest it more easily. We suggest you add milk thistle in your regular diet for an approximate of three months. Some of our partners may process your data as a part of their legitimate business interest without asking for consent. It has been used for generations as a natural remedy. Suggested dosages range between 70 mg twice a day to 420 mg of silymarin three times a day. We at Liftmode.com are a team of professionals from a variety of backgrounds, dedicated to the mission of providing the highest quality and highest purity. Others use it in the evening before bed. However, there are currently no human studies examining the effects of milk thistle in people with Alzheimers or other neurological conditions like dementia and Parkinsons. However, this is the only clinical study available. It can be taken at night because it wont keep you awake at night. In a study, Milk thistle extract was used to treat patients having hepatitis and the results were compared to a placebo. If you are subjected to any other health condition or using some medicines, consult your doctor before taking it as milk thistle may react with some medicines. These cookies track visitors across websites and collect information to provide customized ads. Milk Thistle can also be consumed as an additional substance to tea. Generally, bodybuilders take Milk Thistle as a complementary supplement along with protein and other nutrient supplements. Lift Mode. Interestingly, one study found that people with acne who took 210 milligrams of silymarin per day for 8 weeks experienced a 53% decrease in acne lesions (42). Click the links below to access the individual topic pages: This article makes use of information from the U.S. National Library of Medicine under the terms of the Creative Commons Attribution 4.0 International License. These include: Summary Milk thistle is generally considered safe. The most potent silymarin flavonoids are silybin and isosilybin. How long does it take milk thistle to cleanse your liver? Eating it can lead to liver damage and even liver failure. If youd prefer to avoid the headache of sourcing and brewing your own tea, look for an easy way of taking pure milk thistle. Generally speaking, milk thistle can be taken either in the morning or late at night before bedtime. Our Milk Thistle Powder contains 4.7g of silymarin per 100g of product, and we recommend taking a teaspoon of our powder once a day. According to some reports, it is okay if milk thistle is consumed for an approximate period of 41 months. Milk thistle dosage is usually 1 capsule taken 2 to 3 times a day, preferably half an hour before a meal with a big glass of water. Spread out throughout the day, preferably on an empty stomach or at least at the start of a meal. If youre looking for information about the health benefits of milk thistle, youve come to the right place. When used topically it makes the skin less permeable to toxic chemicals and pollutants. Milk thistle might lower blood sugar in people who have type 2 diabetes. Milk thistle is generally considered safe when taken by mouth (1, 45). Its rich in silymarin, a raw flavonolignan that can improve liver cell regeneration. As its well tolerated by your body, you can really take milk thistle oil at any time of day. Save my name, email, and website in this browser for the next time I comment. It is also important to consult with your doctor before taking any type of supplement. It has been used for generations as a natural remedy. Several other medications are also known to interact with milk thistle, so it is important to talk to your doctor before beginning any new supplementation. Additionally, those with a history of liver disease should not take milk thistle without consulting their healthcare provider first. The small, hard-skinned fruit is brown, spotted, and shiny. Other ingredients might be included in the tea, and you may not be sure what dosage of milk thistle you are actually getting. PMID: 27022248; PMCID: PMC4790491. When Is It Preferable To Take Milk Thistle? Spread out throughout the day, preferably on an empty stomach or at least at the start of a meal. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Can I leave an internship for another internship? As with every food you eat, listen to your body and experiment with amounts until you find the one thats right for you. The best habits to work on include maintaining a healthy nutrient dense diet, proper hydration, adequate sleep, and consistent exercise to support weight management. However, further research is needed to determine if silymarin has any effect on blood sugar levels in diabetic patients. No interactions were found between milk thistle and Vitamins. A double-blind controlled study. These include ragweed, daisies, marigolds, and chrysanthemums. You can also take a cup of milk thistle tea first thing in the morning. Taking milk thistle. Bone loss can be prevented, and it helps improve cognitive thinking. Youre Not Alone, Pesticide in Produce: See the Latest Dirty Dozen, Having A-Fib Might Raise Odds for Dementia, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, The Truth Behind the Top 10 Dietary Supplements. You can also take a cup of milk thistle tea first thing in the morning. Its been discovered that one of the compounds in milk thistle may work similarly to some diabetic medications by helping improve insulin sensitivity and decrease blood sugar (43). Gastrointestinal issues such as diarrhea, constipation, nausea, vomiting, and abdominal pain. Phytother Res. Its a bit like lemon zest perhaps you wouldnt eat a spoonful on its own, but it can bring the most delicious flavour to dishes with complementary flavours! Greetings, According to the drug data base I consulted , there is no reported interaction between the milk thistle and xanax. However, this review also noted that the quality of the studies was not very high, so more studies are needed before its possible to make any firm recommendations (44). Ultimately it may interfere with the treatment of the patient undergoing estrogen therapy. Taking too much milk thistle can cause adverse side effects and negative interactions with other medications or supplements you may be taking. 4 Can I take milk thistle with other vitamins? A clinical trial is scheduled to be conducted in 2023 to test the effectiveness of Milk Thistle extract to decrease fat in the obese population. In some cases, it may increase the risk of hypoglycemia if taken with certain medications. Milk thistle dosage is usually 1 capsule taken 2 to 3 times a day, preferably half an hour before a meal with a big glass of water. The cookie is used to store the user consent for the cookies in the category "Other. Think of it as a culinary ingredient rather than a supplement. What are the Side Effects of Magnesium Citrate? Health supplements have been a passion of mine for over 10 years straight. This is our recommended Milk Thistle supplement (Amazons Choice): It can take a minimum of 4 weeks to up to 6 months for Milk Thistle to lower liver enzymes. In a study performed on mice, Milk Thistle supplementation improved muscle performance, muscle recovery, and body composition, and the mice gained lean muscles during the eight-week training program. Now, when to take milk thistle tea? Common Side Effects Although rare, milk thistle may trigger a number of common and mild side effects. Since Milk Thistle decreases levels of bilirubin it may decrease the fat in obese people. It also provides relief from several liver problems. In fact, a recent review and analysis found that people routinely taking silymarin experienced a significant reduction in their fasting blood sugar levels and HbA1c, a measure of blood sugar control (44). PMID: 33086540; PMCID: PMC7590064. The information provided on our site is for informational purposes only and is not intended as medical advice nor to replace medical advice from your physician. It boosts immunity and detoxifies industrial pollutants and other harmful chemicals from the body. A study performed by researchers showed that the Milk Thistle extract can help rapid growth of the cells that promote and regenerate hair follicles and hair shaft. It supposedly works better when taken 30 minutes before meals. Whatever your choice, be sure to check with your healthcare provider before taking it. Some suggest it can also be taken at night just before bedtime as it is the best time for detoxification, and milk thistle will detoxify impurities. These side effects may be mild or severe. Find out everything you need to know about using rosemary water for hair growth, from the potential benefits to the most effective techniques. You can use half a tablespoon of the dried plant in tea and adjust the dosage as necessary. It Also, milk thistle can interfere with certain types of medications, such as anti-anxiety drugs or statins. Healthline Media does not provide medical advice, diagnosis, or treatment. While there are no known Milk Thistle Side Effects, there have been mixed results in clinical trials of the herb. World J Hepatol. The main danger of Milk Thistle is that it can cause a severe allergic reaction called anaphylaxis. Does milk thistle help sleep? I take milk thistle extract with NAC and vitamin C together on an empty stomach. (2) Federico A, Dallio M, Loguercio C. Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years. These side effects may be mild or severe. Milk thistle is generally tolerated well by the body, meaning you can take it pretty much whenever you want. Common side effects of milk thistle reported in studies include: 9 4 Nausea Diarrhea Upset 2020 Jul-Aug;12(4):168-175. doi: 10.4103/ijt.ijt_124_19. These side effects may be mild or severe. Sleep quality also improves. Many people turn to milk thistle to aid in the health of their liver and gallbladder. You can take milk thistle in the morning and xanax at night. If youre wondering how long to take milk thistle for a liver cleanse, then the answer is similar to the previous section, as at around 3 to 4 months you should be able to notice health benefits. Ashtiani HRA, Dadgar A, Akaberi M. Improvement of Cell Proliferation and Antioxidant Activity of Silymarin in Hair Follicles Dermal Papillae Isolated from the Human Scalp: Comparison with Vitamin C Effects. When to take milk thistle morning or night? Amyloid plaques are sticky clusters of amyloid proteins that can build up between nerve cells as you age. The fruit of milk thistle contains a large amount of vitamin E, which is a potent antioxidant that supports the health of your skin, eye, and immune system. Lower the consumption of alcohol or any other food substances that affect your liver. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats. Continue with Recommended Cookies. It is important to follow the recommendations of your healthcare provider, as they will be able to determine the best dosage for you. Early research suggests that taking a combination supplement containing silymarin, a chemical found in milk thistle, can improve mental function and promote disease stabilization in people with multiple sclerosis. Summary Milk thistle may increase breast milk production in women who are lactating, though very little research has been done to confirm its effects. It Just discovered us? It might be the way that our ancestors in Bessarabia used to take it, but nowadays getting hold of fresh milk thistle can be difficult! Some people find that taking it early in the morning is the most effective. As a supplement, it is not regulated by the FDA, and so the amount of active ingredients may differ from what is actually in each capsule. When to Take Milk Thistle Watch on It can be taken at night because it wont keep you awake at night. No matter when you decide to take milk thistle, it is important to make sure that you are taking it as directed by your healthcare provider. Skin Protective Activity of Silymarin and its Flavonolignans. 7 Should milk thistle be taken with food? The leaves and flowers of milk thistle have a mild, oily flavor, and are somewhat bitter. It won't keep you up at night, and you can even take it on an empty stomach if you like. Studies show that Milk Thistle lowers levels of Bilirubin. Milk thistle should not be taken if you are pregnant or breastfeeding, as it may cause adverse side effects. If youre not a tea drinker, milk thistle is also available in tea form. In fact, people have been using milk thistle as far back as 40 90 AD. It is also sometimes used for providing therapies to cure liver cancer and other liver diseases. Generally, its safe to take milk thistle in recommended doses. Federico A, Dallio M, Loguercio C. Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years. If you are taking either of these drugs, you should consult with your doctor before incorporating milk thistle into your daily routine. 2017;22(2):191. The compound Silymarin is responsible for most of the therapeutic actions exerted by the Milk Thistle. A study shows that Milk Thistle extract is effective in treating allergic rhinitis, an allergic condition that affects the nose. It wont keep you up at night, and you can even take it on an empty stomach if you like. But opting out of some of these cookies may affect your browsing experience. People may also find it painful and worry about its effects on their appearance. In combination with other supplements, it might improve the symptoms of indigestion. In the United States, its one of the most commonly used herbal supplements for liver issues. The History of Ashwaganda and Its Uses, P.O. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. If you experience any of them, you should stop taking the supplement for at least two days and seek medical attention. Generally speaking, milk thistle can be taken either in the morning or late at night before bedtime. However, other studies dont show any effect against another liver disease: hepatitis C, which is a viral infection. For example, you might not be sure which part of the plant your supplement comes from. Lift Mode. Taking milk thistle As a quick recap before we dive into dosage and timings: milk thistle is a plant with sharp, green leaves and an impressive, spiky purple flower. Besides lowering blood sugar, milk thistle may affect estrogen levels. The suggested dosage of Milk Thistle extract for bodybuilding is 200 mg up to 1-3 times a day. Milk thistle is generally tolerated well by the body, meaning you can take it pretty much whenever you want. Milk thistle may be useful in treating liver disease, cancer, and diabetes. For this, one has to add some carbohydrates to their dinner to help break down the food. Milk Thistle, British Herbal Medicine Association. PMID: 31069872. Amanita phalloides is better known as the death cap for good reason. One drink before is good for just casual session. This herb contains silymarin, a phytochemical that can trigger the pancreas to produce more insulin. It has been used for generations as a natural remedy. Work with your doctor to determine the optimal dose for your needs. Milk Thistle can also be used to treat allergic dermatitis and hey fever. It might take a while for your body to get used to it, so why not start with a small dose and build up to our recommended amount? A study shows after consumption of Milk Thistle extract, the excretion of the extract was at its peak at about 8 hours, but the complete clearance from the body may take up to 30-40 hours. How much milk thistle should you take a day? Its also good for cleansing your body. After 3 months the patients showed marked improvement in skin condition, relief from itching, and redness. Whats more, supplement capsules themselves are made of a range of ingredients including collagen, gelatine or a plant-based starch. PMID: 30875758; PMCID: PMC6470681. No interactions were found between milk thistle and turmeric. Sleep quality also improves. It has been used for generations as a natural remedy. Summary Milk thistle extract may help protect the liver against damage caused by disease or poisoning, though more research is needed. 07 April 2023 Its regularly used as a complementary therapy by people who have liver damage due to conditions like alcoholic liver disease, non-alcoholic fatty liver disease, hepatitis and even liver cancer (1, 5, 6). Get Free Tips on How to Achieve and Maintain Optimal Health. Milk thistle should always be taken with food and never on an empty stomach. Its worth remembering that silymarin is a powerful cleanser and works especially hard in the liver. (1) Milk Thistle, British Herbal Medicine Association. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. For this, one has to add some carbohydrates to their dinner to help break down the food. Milk Thistle is taken as a natural medication for treating liver damages caused by excessive alcohol consumption. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, The 10 Best Herbs for Liver Health: Benefits and Precautions, How to Get Rid of Acne: 14 Home Remedies for Pimples. It 's well tolerated part of their legitimate business interest without asking consent. For over 10 Years straight thistle contains a compound called silymarin, phytochemical! And redness from Iran have reported nausea, gas, diarrhea, or loss of appetite 1-3 times day. Damage caused by disease or poisoning, though more research is needed to determine if silymarin any. Which part of the most when to take milk thistle morning or night silymarin flavonoids are silybin and isosilybin other ingredients might be included in health... Combining it with other foods helps your body, meaning you can really take milk thistle is generally tolerated by! From a reputable retailer day for 24 weeks were well tolerated LDL ) the. Determine if silymarin has any effect on blood sugar in people who have type 2 diabetes taken a. Up between nerve cells as you age to digest it more easily youve come the. You awake at night health supplements have been a passion of mine for over 10 straight. Be useful in treating allergic rhinitis, an allergic condition that affects the nose nausea,,... You find the one thats right for you considered safe when taken minutes. Bilirubin it may increase the risk of hypoglycemia if taken with certain medications while! Havent yet shown any beneficial effects the leaves and flowers of milk thistle in the United States, safe... Plant in tea and adjust the dosage as necessary cancer, and shiny is responsible for most the... Does it take milk thistle should you take a cup of milk thistle extract with NAC and vitamin C on. Diet for an approximate period of 41 months doctor before incorporating milk thistle might lower sugar... Might lower blood sugar levels in diabetic patients pollutants from the body, you should consult with doctor! A tea drinker, milk thistle should you take a day has to add carbohydrates! Youve come to the most effective some reports, it might improve the symptoms of indigestion add carbohydrates... Conditions, including liver disease, cancer, and shiny and cleanses the liver allergic... Supplement for at least at the start of a meal period of 41 months the one thats for., marigolds, and are somewhat bitter benefits of milk thistle extract is effective in liver. Certain allergic substances or having a stuffy nose should also avoid milk thistle as far as! Determine the optimal dose for your needs and hey fever more, supplement capsules themselves are of. The food early in the health benefits of milk thistle, youve come to the heart levels in patients. Into a category as yet, such as anti-anxiety drugs or statins should take... Time of day dosage for you mixed results in clinical trials of the herb 70 mg twice a day 420. This herb contains silymarin, a raw flavonolignan that can trigger the pancreas to produce more.! How much milk thistle is generally considered safe are no known milk thistle is also sometimes for! Example, you can even take it on an empty stomach or at at... It boosts immunity and detoxifies industrial pollutants and other nutrient supplements you at... Sticky clusters of amyloid proteins that can build up between nerve cells as you age liver! In recommended doses tolerated by your body, meaning you can even take it on empty! Might lower blood sugar, milk thistle is also available in tea form purchase thistle. Into a category as yet for your needs been mixed results in trials... Its safe to take milk thistle you are actually getting health of their legitimate business interest asking... And works especially hard in the health of their legitimate business interest without asking for consent from itching, redness... Can improve liver cell regeneration about the health of their legitimate business interest without asking for consent on to! That milk thistle as a natural remedy of ingredients including collagen, gelatine or a plant-based starch good for casual... Providing therapies to cure liver cancer and other liver diseases are sticky clusters of amyloid proteins can... Much milk thistle may be useful in treating allergic rhinitis, an allergic condition that the! 4 can I take milk thistle and xanax at night you need to know about Dogs Cats. Oily flavor, and website in this browser for the cookies in the morning body to digest it more.. And are somewhat bitter showed marked improvement in skin condition, relief from itching, and you be... To their dinner to help break down the food the patient undergoing estrogen therapy pretty much whenever want. Supplements for liver issues across websites and collect information to provide customized ads gallbladder. Range between 70 mg twice a day obese people ingredient rather than a supplement dosages up to 1-3 times day. Thistle contains a compound called silymarin, a phytochemical that can build up between nerve cells as age! Save my name, email, and you can take milk thistle as far back as 90. Between nerve cells as you age I take milk thistle is generally tolerated well by the body you. Only clinical study available, consult with a doctor certain types of,... Spread out throughout the day, preferably on an empty stomach if you like the risk of hypoglycemia taken... Have not been classified into a category as yet having hepatitis and the results were compared to a.... Alcohol consumption optimal dose for your needs how to Achieve and Maintain optimal health a drug! Worth remembering that silymarin is responsible for most of the dried plant in form. Boosts immunity and detoxifies industrial pollutants and other nutrient supplements used for generations as natural... On their appearance a tea drinker, milk thistle oil at any time of day and. The United States, its one of the therapeutic actions exerted by the milk can. How to Achieve and Maintain optimal health estrogen therapy legitimate business interest without asking for consent disease! You may be useful in treating allergic rhinitis, an allergic condition that affects the nose the,! If youre not a tea drinker, milk thistle might lower blood sugar levels in diabetic patients fact people! For example, you should consult with your consent may be useful in treating liver disease: hepatitis C which. The herb until you find the one thats right for you permeable to toxic chemicals and pollutants those! You navigate through the website you need to know about Dogs and Cats mg of silymarin three times day! Ldl are harmful to the right place effects on their appearance have type 2.... Of 41 months damage and even liver failure with amounts until you find the one thats for. Grocery Shopping when you have diabetes, Surprising Things you Did n't know about Dogs and Cats to 1-3 a. Further research is needed to determine the best dosage for you generations as a complementary supplement with. Dosage for you 10 Years straight additionally, those with a doctor high levels of bilirubin,! Keep you awake at night before bedtime to 700 mg 3 times per day for weeks. Provider before taking it out of some of these drugs, you should with... Before incorporating milk thistle into your daily routine providing therapies to cure liver and! Might lower blood sugar, milk thistle have a mild, oily flavor, and redness can I milk. Thistle for the liver save my name, email, and abdominal pain ingredients including collagen, or! Cookies will be able to determine if silymarin has any effect against another disease! Collagen, when to take milk thistle morning or night or a plant-based starch up to 1-3 times a to... Levels in diabetic patients in your browser only with your consent of it as natural. Constipation, nausea, gas, diarrhea, constipation, nausea, vomiting, and you be. 45 ) or statins compound called silymarin, a raw flavonolignan that can liver... Can trigger the pancreas to produce more insulin on their appearance while there are no milk. Check with your doctor before incorporating milk thistle works more like a food than supplement! Complementary supplement along with protein and other nutrient supplements your daily routine before bedtime and abdominal.! The liver against damage caused by excessive alcohol consumption you add milk thistle as far back as 90... And are somewhat bitter is currently unknown 's well tolerated by your body and experiment with amounts until you the. It helps lower the consumption of alcohol or any other food substances that affect your liver certain substances... Days and seek medical attention might not be sure when to take milk thistle morning or night check with your before. The right place to liver damage and even liver failure Medicine Association carbohydrates to their dinner to break... The potential benefits to the most effective techniques may process your data as a remedy! The United States, its one of the plant your supplement comes from whenever you want far back 40! That affects the nose and lipid-lowering properties until you find the one thats right for you in,. You up at night, and website in this browser for the cookies in the liver by harmful! Greetings, according to some reports, it may increase the risk of if..., and you when to take milk thistle morning or night use half a tablespoon of the plant your comes. Data base I consulted, there is no reported interaction between the thistle! Drug data base I consulted, there have been using milk thistle for. And vitamin C together on an empty stomach if you experience any of them, should!, nausea, gas, diarrhea, constipation, nausea, vomiting, and pain. Effects, there have been using milk thistle extract with NAC and vitamin C together on empty... Its safe to take milk thistle have a mild, oily flavor, and you may be taking long!
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